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1


What specific markers were used to assess the purity of the STEM-PD batch?

These markers identify midbrain dopaminergic progenitor cells and confirm that the stem cells were successfully differentiated into the desired cell Cell marker analysis is commonly used in stem cell research to verify cell identity and purity. 7

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2


What is the primary function of AI in the medical imaging industry?

To improve diagnostic accuracy and patient outcomes

AI can quickly analyze medical images, detect abnormalities, and assist healthcare professionals in making faster and more accurate diagnoses. Ai in medical imaging and use machine learning which enables computers to recognize patterns in medical images. 7

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3


Which of the following is a key benefit of AI in radiology noted in the article?

Acts as a second medical opinion

Ai helps radiologists analyze medical images by identifying abnormalities and highlighting them to the radiologist. These technologies assist radiologists by recognizing patterns in medical images. 7

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4


What does AI literacy refer to according to the article?

Understanding and knowledge of AI technology

AI literacy refers to understanding and knowledge of AI technology. It Include knowing how ai works , its benefits and limitations. It emphasized knowledge and skills need to understand and evaluate the technology. 7

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5


Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?

The color of the AI machines

The color of ai machines does not influence the Ai among healthcare professionals. People are more likely to accept and use new technology when they find it useful. 7

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6


What role does social influence play in AI acceptability in healthcare according to the article?

Determines the financial budget for AI

Social affects healthcare professionals decisions to us ai as a supporting tool. Social influence is an important factor affecting whether people accept and use new technology new technologies or not. 7

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7


What is a perceived threat regarding AI usage in healthcare settings?

Concerns about replacing healthcare professionals

Some healthcare worker are concerned ai might took over their job but ai would only support healthcare professionals by improving decision making People suggest that perceived threats and concerns can reduce people’s willingness to accept and use new technologies 7

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8


According to the article, what is essential for increasing AI acceptability among medical professionals?

Designing human-centred AI systems

It is essential for increasing Ai acceptability among medical professionals.ai should be easy to use. Ai is more likely to be accepted when it is useful, easy to use, and supports rather then replaceing healthcare professionals. 7

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9


What does the 'system usage' category of AI acceptability factors include according to the article?

Factors like value proposition and integration with workflows

system usage category includes factors such as the value proposition of AI and its integration with existing clinical workflows. User are more likely to adopt technology when they perceive it as useful and easy to use. 7

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10


How does ethicality impact AI acceptability among healthcare professionals?

Affects views on AI based on compatibility with professional values

Whether healthcare professionals believes Ai aligns with their professional values and ethical responsibilities or not. Ai ethics suggest that healthcare professionals are more willing to use Ai when it is as a ethical standards. 7

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11


What methodological approach did the article emphasize for future AI acceptability studies?

Considering user experience and system integration deeply

future AI acceptability studies should consider user experience and system integration in depth. Researcher suggest that technology is more likely to be accepted when it is designed to meet user need while integrating.. 7

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12


What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?

To replace lost dopamine neurons.

Parkinson’s disease causes the degeneration of dopamine-producing neurons, leading to movement problems such as tremors and slow movement. Stem cell therapy aims to repair or replace damaged cells and tissue. 7

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13


Which animal was used to test the STEM-PD product for safety and efficacy?

Rats

Rat are used because they could hold Parkinson’s disease symptoms and help researchers. New treatment are first tested in animal model to evaluate their safety and effectiveness before processing to trials in humans. 7

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14


What was the duration of the preclinical safety study in rats mentioned in the article?

9 months

This duration allowed researchers to monitor the long-term safety of the transplanted cells. Preclinical studies requires long-term evaluation of a treatment’s safety and effectiveness in animal models before clinical testing in humans. 7

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15


What is the name of the clinical trial phase mentioned for STEM-PD?

Phase I/IIa

focuses on evaluating both safety and preliminary efficacy. This phase is used in early human trials to determine whether the treatment is safe or is danger to human. It allows researchers to effectiently assess safety while gathering evidence. 7

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16


How is the STEM-PD product manufactured?

Under GMP-compliant conditions

GMP-compliant conditions to ensure safety, consistency, and quality. GMP standards regulate how stem cell products are produced and processed for clinical use in human. GMP is a regulatory framework used in biomedical and pharmaceutical production. It ensures that advanced therapies like stem cell products. 7

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17


According to the article, what confirmed the safety of the STEM-PD product in rats?

The safety of the STEM-PD product in rats was confirmed by the absence of adverse effects and no tumor formation. This indicates that the transplanted stem cell-derived dopamine neurons were well tolerated A lack of tumor formation and negative side effects is a key indicator that a cell therapy product is safe enough to proceed toward clinical trials. 7

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18


What key finding was noted in the efficacy study of STEM-PD in rats?

Transplanted cells reversed motor deficits in rats.

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19


What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?

They are used in cell patterning for specific neural fates.

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20


What was a key outcome measured in the preclinical trials for efficacy in rats?

Development of new cognitive abilities

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ผลคะแนน 102.95 เต็ม 140

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