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1


What specific markers were used to assess the purity of the STEM-PD batch?

FOXA2 and OTX2

These two markers were use to assess the purity of the STEM-PD batch by confirm the ventral midbrain. Development in biology theory, The developments of FOXA2 and OTX2 is a first step on developing a better development in biology field and it will contribute a greater goood in the future. 7

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2


What is the primary function of AI in the medical imaging industry?

To improve diagnostic accuracy and patient outcomes

The AI will improve the dianostic accuracy and patients outcomes. The study shows that AI will help enhance the accuracy in disgnosting in radiology. The theory of AI-innovation. The Ai innovation will serve as a tools for helping the doctor to decide and make the decision for the futher medical process. 7

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3


Which of the following is a key benefit of AI in radiology noted in the article?

Acts as a second medical opinion

The study shows that AI will be serve as the tools for doctor to help decide and enhance the diagnosis. The AI will give the doctor ANOTHER opinion so the doctor will have both his/her opinion and the ai opinion and it will enhancs the doctor choice making. The AI-tools theory. AI will possibly be the doctor 2nd opinion when diagnosing the patients diagnostic not just in radiology but almost in every medical field. 7

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4


What does AI literacy refer to according to the article?

The ability to repair AI machines

The doctor should understand and look at AI in the perspective if it being "tools" and not something that will disrupt their occupation. Also they should admit that AI knowledge is also as good as their knowledge and if both parties work together it will enchance the efficiency in medical field. The theory of AI knowledge and it's ethic is apllies in this question because the doctor should understand ai and look at it as tools. Also AI also need to have an ethic (if possible) because when it comes to medical field ethic play a great role in this field. 7

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5


Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?

The color of the AI machines

The physical apperence doesn't affect the performance of the AI machines itself. The physical apperence theory shows that the apperence of a subject of things doesn't affect the performance of the subject itself. The color of the ai machines being on of the example. 7

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6


What role does social influence play in AI acceptability in healthcare according to the article?

Affects healthcare professionals’ decisions to use AI

The social influence the professionals decision to use ai and the acceptabilit in healtcare because the society doesn't have a high rate of acceptablity in AI being serve as a tools due to the study. It has been told in the study that people doesn't really trust the AI that's why the acceptability rate is low. The trust theory. This theory shows that most people in our society today still doesn't trust the AI fully. 7

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7


What is a perceived threat regarding AI usage in healthcare settings?

Concerns about replacing healthcare professionals

The concerns about replacing healthcare professinals is a very big topic the were discuss amoung the medical community. Many doctor or healthcare professionals are concerns that AI usage will disrupt their occupation making the role of doctor less than ai. One of the example is that Elon Musk have said that " studying doctor will no longer be important". He said that because the is going to repleace the doctor with his robot, but things that AI doesn't have is empathy, love, emotion, and ethic and this will make doctor to continue their legacy in their job and AI will only be their tools. The theory of AI threat toward healthcare professionals, this theory shows that some healthcare professional still concern about this topic and they should see AI only as a tools in enhancing the medical field. 7

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8


According to the article, what is essential for increasing AI acceptability among medical professionals?

Designing human-centred AI systems

This study suggest that if AI were to be increase in the medical field. The things that have to be change is the work of how AI work. The study pursued that AI should be deisgning "human-like" or AI that is centred human. They do not want AI to only think in an algorithmic perfarmance but also in human way aswell. The theory of ethic and emotion in ai designing. This theory shows that AI should be deisgn in a way that it can compute in a way human computed in order to create a safe and efficient diagnositic. 7

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9


What does the 'system usage' category of AI acceptability factors include according to the article?

Factors like value proposition and integration with workflows

The article said that Ai should create a good workflows in the hospital and not make interruption to the workplaces. Ai being a value proposition is also important becasue the ai will sever and diagnostic tools to help the doctor. The theory of workflow intergation is used in this question and article because ai should very much go with the flow the in hospital to create a flowing workingstate and efficient performance in the hospital. 7

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10


How does ethicality impact AI acceptability among healthcare professionals?

Affects views on AI based on compatibility with professional values

The ai acceptability among healthcare professionals is ethicality impact in terms of affecting views on ai based on compatibility with professional values. Ai and doctor will work together as one and it will relies on one another The compatibility theory. This theory shows that the compatibility between ai and doctor will create and ethic discussing and diagnostic while working. 7

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11


What methodological approach did the article emphasize for future AI acceptability studies?

Considering user experience and system integration deeply

In the future, if ai acceptability in hospital is high. This study shows that they hospital should consider the user experience with the ai toold and system intergration deeply because the user or patients feedback will help the hospital decide weather ai tools should be continue or not. The user feed back will also improve the improvement of the ai itself. The theory of use feedback. In almost every product user feedback is very important and this will do the same if the hospital start to use ai in the workplace. 7

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12


What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?

To replace lost dopamine neurons.

The primary objective of using hESC in treating Parkinson's disease is because they wish to replace the lost dopamine neurons in the patients brain. Pakinson's disease is when the brain lost dopamine neurons in the substantia nigra and the primary objective is to use hESC to make a stem cell that can produce the dopamine neurons. Pakinson's disease cause primary from the lost of dopamine neurons in substantia nigra and the theory of hESC in very important aswell because hESC is pluripotent which mean it can change into any cell type. 7

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13


Which animal was used to test the STEM-PD product for safety and efficacy?

Rats

Rats is used to test in STEM-PD because it a very first animal to use in this testing because it is a very small animal with high productivity rate. However the reseach should also respect the rats and they need to try to make every of them survive because the ethic of being reseacher is to take the participle safety first. The theory of rats being the testing subject. The many research rats is consider a very common subject being use for testing. Due to their size and population that is why they are quite popular amoung the reseach testing. 7

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14


What was the duration of the preclinical safety study in rats mentioned in the article?

9 months

When testing the safety of tumorigenicity in the pre-clinic. It takes 9 months of observation of the rate to make sure that it's safe and cause no tumorigenicity. theory of obervation, this thoery shows that when conducting a reseach like this STEM CELL-PD observation is very important and reseach should use high duration of time to observer to outcome to make sure that they are safe. 7

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15


What is the name of the clinical trial phase mentioned for STEM-PD?

Phase I/IIa

There are 2 phrase which the the phrase I that use 1 dose and the phrase II that uses 2 dose 7

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16


How is the STEM-PD product manufactured?

Under GMP-compliant conditions

The stem-ped product have to goes under the GMP in order to create a trustworthy product and the GMP is a very standard way in manufacturing a medical or biological product. 7

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17


According to the article, what confirmed the safety of the STEM-PD product in rats?

There were no adverse effects or tumor formation.

The reseach confirmed that there were no tumorigenicity when testing in rat which mean that there are no toxicity or toxin in the rats and it can be use to authorisation ro ATMP to test in human 7

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18


What key finding was noted in the efficacy study of STEM-PD in rats?

Transplanted cells reversed motor deficits in rats.

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19


What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?

They are used in cell patterning for specific neural fates.

7

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20


What was a key outcome measured in the preclinical trials for efficacy in rats?

Recovery of motor function

The recovery of rat should always be real-time monitorize 7

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ผลคะแนน 113.65 เต็ม 140

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