| 1 |
What specific markers were used to assess the purity of the STEM-PD batch?
|
FOXA2 and OTX2 |
|
FOXA2 And OTX2 describe the STEM-PD batch is purity. |
Purity/Identity Markers (Target Cells): The main specification requires that ≥70% of the cell population is positive for FOXA2 and OTX2. In GMP-manufactured batches, this value was typically 87%–99%. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 2 |
What is the primary function of AI in the medical imaging industry?
|
To improve diagnostic accuracy and patient outcomes |
|
It can replace the old medical tool and it has more efficiency . |
The primary function of AI in the medical imaging industry is to enhance the accuracy, speed, and efficiency of image analysis and interpretation. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 3 |
Which of the following is a key benefit of AI in radiology noted in the article?
|
Acts as a second medical opinion |
|
AI in radiology can comment the opinion in diagnosis. |
It assists radiologists by detecting subtle pathologies, automating routine tasks like segmentation, reducing scan times, and prioritizing urgent cases to improve diagnostic efficiency and patient outcomes. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 4 |
What does AI literacy refer to according to the article?
|
Understanding and knowledge of AI technology |
|
AI literacy refers to the understanding and knowledge of AI technology, including how it works, how to use it effectively, and how to critically evaluate its impact and limitations. |
According to articles from The Conversation and other sources, AI literacy involves fundamental competencies encompassing knowledge, skills, and attitudes required to critically understand, evaluate, and use artificial intelligence technologies safely and effectively in various aspects of life. Key elements include understanding AI concepts, critical evaluation of tools, ethical usage, and effective collaboration with AI systems. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 5 |
Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?
|
The color of the AI machines |
|
The factor that is NOT listed as influencing the acceptability of AI among healthcare professionals is The Color of the AI Machines, because acceptability is mainly influenced by trust, system understanding, workflow integration, and technology receptiveness. |
The literature has converged towards three overarching categories of factors underpinning AI acceptability including: user factors involving trust, system understanding, AI literacy, and technology receptiveness; system usage factors entailing value proposition, self-efficacy, burden, and workflow integration; and socio-organisational-cultural factors encompassing social influence, organisational readiness, ethicality, and perceived threat to professional identity. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 6 |
What role does social influence play in AI acceptability in healthcare according to the article?
|
Affects healthcare professionals’ decisions to use AI |
|
Social influence affects healthcare professionals’ decisions to use AI by shaping their attitudes and intentions toward adopting the technology. |
Social influence significantly impacts the adoption and acceptance of artificial intelligence (AI) in healthcare, acting as a key predictor of technology acceptance behavior. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 7 |
What is a perceived threat regarding AI usage in healthcare settings?
|
Concerns about replacing healthcare professionals |
|
A perceived threat regarding AI usage in healthcare is concerns about replacing healthcare professionals, which can reduce acceptance and trust in AI systems. |
Perceived threats regarding AI in healthcare center on patient safety risks from unpredictable errors, data privacy breaches, and ethical concerns like algorithmic bias. Key fears include reduced human interaction, over-reliance on technology leading to deskilling, job displacement, and diminished medical authority. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 8 |
According to the article, what is essential for increasing AI acceptability among medical professionals?
|
Designing human-centred AI systems |
|
Designing human-centred AI systems is essential for increasing AI acceptability among medical professionals because it ensures trust, usability, transparency, and proper integration into clinical workflows. |
Explainable AI (XAI) reduces the "black box" concern, allowing clinicians to understand, trust, and rely on AI-driven decisions. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 9 |
What does the 'system usage' category of AI acceptability factors include according to the article?
|
Factors like value proposition and integration with workflows |
|
The “system usage” category includes factors such as value proposition and integration with existing workflows, which determine how effectively AI fits into clinical practice. |
the "system usage" category of AI acceptability factors entails the value proposition, self-efficacy, burden, and workflow integration. These factors specifically relate to how the AI fits into day-to-day operations and the effort required for adoption, rather than just the technology's capability. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 10 |
How does ethicality impact AI acceptability among healthcare professionals?
|
Affects views on AI based on compatibility with professional values |
|
Ethicality affects AI acceptability by influencing whether healthcare professionals perceive AI as compatible with their professional and ethical values. |
Ethicality is a primary determinant of artificial intelligence (AI) acceptability among healthcare professionals, acting as a gatekeeper for adoption. While professionals recognize AI's potential to improve diagnostics and efficiency, their willingness to use it is heavily contingent on the technology adhering to core ethical principles—specifically transparency, accountability, bias mitigation, and patient privacy. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 11 |
What methodological approach did the article emphasize for future AI acceptability studies?
|
Considering user experience and system integration deeply |
|
The article emphasized that future studies should deeply consider user experience and system integration to better understand AI acceptability in healthcare. |
There is an increasing worldwide interest and investment in the application of Artificial Intelligence (AI), and the dental field is no exception. AI shows promise in all dental disciplines. However, uptake in clinical practice is slow, and there is limited understanding of users’ acceptability in the Netherlands. This study aims to provide insights into the acceptability of Dutch dental professionals and students regarding AI in the dental field. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 12 |
What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?
|
To replace lost dopamine neurons. |
|
The primary objective of using human embryonic stem cells in treating Parkinson’s disease is to replace lost dopamine neurons and restore dopamine production.
|
The primary objective of using human embryonic stem cells (hESCs) in treating Parkinson’s disease is to replace the dopamine-producing neurons that have died or become dysfunctional in the midbrain (substantia nigra). |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 13 |
Which animal was used to test the STEM-PD product for safety and efficacy?
|
Rats |
|
In the experiment is used the rat. |
The rat is the common experimental animal. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 14 |
What was the duration of the preclinical safety study in rats mentioned in the article?
|
6 months |
|
In preclinical research involving human embryonic stem cells for Parkinson’s disease, a six-month study in rats is commonly conducted to evaluate. |
A six-month period is considered sufficient in rodent models to assess mid- to long-term safety before proceeding to human clinical trials.
|
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 15 |
What is the name of the clinical trial phase mentioned for STEM-PD?
|
Phase I |
|
A Phase I trial is the first stage of testing a new treatment in humans. |
At this stage, the focus is not primarily on effectiveness, but on ensuring the treatment is safe enough to proceed to later phases (Phase II and III), which evaluate efficacy more extensively. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 16 |
How is the STEM-PD product manufactured?
|
Under GMP-compliant conditions |
|
STEM-PD is manufactured under GMP-compliant conditions to ensure safety, quality, and regulatory approval for clinical use. |
The STEM-PD product is manufactured using a Good Manufacturing Practice (GMP)-compliant, scalable process that differentiates human embryonic stem cells (hESCs) into dopamine-producing progenitor cells. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 17 |
According to the article, what confirmed the safety of the STEM-PD product in rats?
|
There was increased tumor formation. |
|
The safety of the STEM-PD product in rats was confirmed because there were no adverse effects or tumor formation. |
The safety of the STEM-PD product (a human embryonic stem cell-derived dopaminergic progenitor cell therapy) in rats was confirmed through a 39-week GLP (Good Laboratory Practice) safety study. This comprehensive, long-term study in immunodeficient (nude) rats demonstrated that the product did not cause adverse effects or tumor formation. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 18 |
What key finding was noted in the efficacy study of STEM-PD in rats?
|
No cells survived post-transplant. |
|
It demonstrates they not have a disease. |
The grafts matured and integrated into the host brain, leading to a complete, full functional reversal of motor symptoms. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 19 |
What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?
|
They are used in cell patterning for specific neural fates. |
|
Growth factors like FGF8b and SHH are used to pattern stem cells toward specific neural fates, particularly midbrain dopaminergic neurons needed for Parkinson’s disease treatment. |
In the manufacturing process of STEM-PD (a stem cell-based therapy for Parkinson's disease), growth factors like FGF8b (Fibroblast Growth Factor 8b) and SHH (Sonic Hedgehog) are essential signaling molecules used to differentiate human pluripotent stem cells (hPSCs) into functional midbrain dopaminergic (mDA) neurons. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|
| 20 |
What was a key outcome measured in the preclinical trials for efficacy in rats?
|
Recovery of motor function |
|
A key outcome measured for efficacy in rats was recovery of motor function.
|
A key outcome measured in preclinical efficacy trials in rats is Tumor Growth Inhibition (TGI), particularly in oncology studies, where it serves to measure how much a treatment reduces tumor volume or weight compared to a control group. |
7 |
-.50
-.25
+.25
เต็ม
0
-35%
+30%
+35%
|