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1


How does the concept of “model as a dataset” reshape traditional data-sharing practices in medical imaging?

3. It enables sharing of learned model weights instead of sensitive raw images.

Seems the most logical, generative AI still requires approval from medical experts incase of glitches. With the sharing of model weights, the AI can learn more about different types of problems. 7

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2


Which analytical conclusion can be drawn about the trade-offs between physics-informed and statistical models?

2. Physics-informed models are more interpretable but computationally intensive.

The rest of the choices are false. Choice 2 is the most reasonable. Physics- informed model uses theoretical correct mathematical equations and the principle of physics. 7

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3


Why is “mode collapse” considered a critical problem in GAN-based medical image synthesis?

2. It reduces image realism and variety by producing repetitive outputs.

Mode collapse doesn’t fit some of the choices. “The GANs excel at generating high-quality samples but might not always capture all data variations, leading to low mode coverage, known as mode collapse.” 7

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4


Why are healthcare-specific metrics preferred over general-purpose metrics such as FID or SSIM?

2. They better capture clinical accuracy and diagnostic relevance.

FID and SSIM only evaluate the quality of the generated image. Panel 2: Exploring the potential of generative artificial intelligence in medical image synthesis: opportunities, challenges, and future directions. 7

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5


What does the article identify as the key tension between privacy preservation and image fidelity?

1. Higher realism may risk reproducing identifiable patient data.

Generative AI is still under exploration. The risk if data copying on another patient is likely. The article stated that one of the biggest challenges on privacy is data copying. 7

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6


Why is the FDA’s approval of synthetic MRI technology significant for future AI-generated data?

1. It establishes a framework for validating synthetic data equivalence in clinical use.

All the answers wasn’t mentioned in the article. The FDA and the European Medicines Agency “will play a crucial role in establishing frameworks for validating and approving synthetic data for clinical applications.” - from the article. 7

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7


Which strategy would best mitigate demographic bias in generative models according to the article?

1. Increasing sampling from majority populations

The other choices are actually supporting the demographic bias in generative models. Future research directions: “Establishing multi-institutional collaboratives to create demographically balanced training data.” 7

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8


How do DDPMs exemplify versatility in healthcare image synthesis?

2. They can perform multiple tasks such as denoising, inpainting, and anomaly detection without retraining.

The list of multiple tasks in choice 2. all describes the strengths of DDPMs. “DDPMs generate data by learning to reverse a noising process.” “DDPMs can produce high quality samples that closely resemble the training data.” 7

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9


What analytical insight does the article provide about integrating AI-generated medical images into education and research?

2. It enhances training by providing diverse, realistic datasets without ethical breaches.

Most logical Generative AI has large sets of data on basically everything, students can use the database to study deeper into specific topics. 7

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10


Why is regional calibration essential when applying risk prediction models across countries?

2. To adjust for population-specific incidence and lifestyle differences

People live in different regions and have different lifestyles. Genetic variation plays a huge role in how people get affected, some are born with genetic disadvantages. 7

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11


What analytical conclusion can be drawn when comparing the China-PAR and Framingham models?

2. China-PAR uses local epidemiological data, leading to improved predictive validity.

From the article, China-PAR is created for the Chinese population. While Framingham is used over a 10 year risk assesment. China-PAR includes several factors like ancestral trial and lifestyle. 7

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12


Based on CVD mortality data, what analytical inference can be made about Japan’s position compared to neighboring countries?

1. Japan’s low CVD mortality suggests effective prevention and healthcare systems.

Japan’s healthcare system is effective. Japan prevention is why the mortality rate is low. 7

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13


What analytical limitation arises when using Western-derived coefficients in East Asian models?

2. It introduces systematic overestimation of ASCVD probability.

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14


What policy implication can be derived from country-specific risk models?

1. They allow for targeted national prevention programs.

For ASCVD, you can’t generalize the data. The data differed from all countries and regions. 7

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15


If a model excludes socioeconomic variables, what analytical consequence might occur?

2. Ignored non-biological determinants of disease

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16


How might AI improve next-generation ASCVD risk prediction in East Asia?

2. By integrating multimodal data, including imaging and lifestyle information

AI is smart and can use all the data ever on the internet to assess. AI can possibly create a formula linking to dietary, lifestyles and other factors. 7

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17


What conclusion can be drawn from comparing Mongolia’s and South Korea’s CVD mortality rates?

2. Both have identical age-adjusted mortality rates.

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18


What is the most logical future direction for improving ASCVD models across East Asia?

1. Establishing multinational data-sharing platforms to harmonize regional models

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19


According to the “image generation trilemma” shown in the figure, what analytical conclusion can be drawn about the relative strengths of VAEs, GANs, and DDPMs in medical image synthesis?

2. GANs provide a balance between image quality and diversity but may suffer from mode collapse.

GANs is described perfectly. The article shows that GANs is perfect for image enhancing. 7

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20


Based on Figure, what analytical conclusion can be drawn regarding the distribution of cardiovascular disease (CVD) subtypes across East Asian countries?

1. Ischemic heart disease (IHD) accounts for a higher proportion of CVD deaths in Japan and South Korea compared with China, suggesting regional lifestyle or prevention differences.

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ผลคะแนน 99.3 เต็ม 140

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