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1


What is the primary function of AI in the medical imaging industry?

To improve diagnostic accuracy and patient outcomes

AI helps doctors detect diseases more accurately and faster from medical images, improving patient care. Computer-aided diagnosis uses AI to reduce human error and support medical decisions. 7

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2


Which of the following is a key benefit of AI in radiology noted in the article?

Acts as a second medical opinion

AI acts as a second opinion by assisting radiologists in reviewing images, which helps reduce errors and improve diagnosis accuracy. This follows the concept of computer-aided diagnosis, where AI supports human decision-making to enhance reliability. 7

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3


What does AI literacy refer to according to the article?

Understanding and knowledge of AI technology

AI literacy means having basic understanding and knowledge about how AI works and its applications, enabling informed use and decision-making. Based on the concept of digital literacy, AI literacy empowers users to interact effectively with AI technologies. 7

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4


Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?

The color of the AI machines

The color of AI machines is irrelevant to healthcare professionals’ acceptance; key factors involve trust, integration, understanding, and openness to technology. Technology Acceptance Model (TAM) emphasizes perceived usefulness and ease of use, not superficial features like color. 7

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5


What role does social influence play in AI acceptability in healthcare according to the article?

Affects healthcare professionals’ decisions to use AI

Social influence impacts how healthcare professionals decide to adopt AI based on peers, leaders, and social norms. This is supported by the Unified Theory of Acceptance and Use of Technology (UTAUT), highlighting social influence on technology adoption. 7

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6


What is a perceived threat regarding AI usage in healthcare settings?

Concerns about replacing healthcare professionals

A common perceived threat is that AI might replace healthcare professionals, causing job insecurity and resistance to adoption. Based on Technology Acceptance Model, perceived threats affect users’ willingness to accept new technologies. 7

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7


According to the article, what is essential for increasing AI acceptability among medical professionals?

Designing human-centred AI systems

Human-centred AI designs focus on usability and collaboration with healthcare professionals, increasing trust and acceptance. User-centred design principles highlight the importance of aligning technology with user needs to improve adoption. 7

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8


What does the 'system usage' category of AI acceptability factors include according to the article?

Factors like value proposition and integration with workflows

System usage includes how well AI fits into existing workflows and the value it provides to users, influencing acceptance. Technology Acceptance Model highlights perceived usefulness and ease of integration as key to adoption. 7

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9


How does ethicality impact AI acceptability among healthcare professionals?

Affects views on AI based on compatibility with professional values

Ethicality influences whether healthcare professionals accept AI based on how well it aligns with their professional and moral values. Ethical Acceptance Theory emphasizes the role of value congruence in technology adoption. 7

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10


What methodological approach did the article emphasize for future AI acceptability studies?

Considering user experience and system integration deeply

Future studies should focus on how users interact with AI and how well AI integrates into healthcare workflows to improve acceptance. User-Centred Design and Technology Acceptance Model stress the importance of user experience and system fit. 7

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11


What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?

To replace lost dopamine neurons.

Human embryonic stem cells can differentiate into dopamine-producing neurons, which are lost in Parkinson’s disease, helping restore brain function. Stem cell therapy aims to replace damaged cells to restore normal function. 7

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12


Which animal was used to test the STEM-PD product for safety and efficacy?

Monkeys

Monkeys are used because their brain structure and function closely resemble humans, making them ideal for testing safety and efficacy. Non-human primate models provide relevant insights into human neurological diseases and treatment responses. 7

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13


What was the duration of the preclinical safety study in rats mentioned in the article?

12 months

A 12-month preclinical study in rats provides sufficient time to observe long-term safety and potential side effects. Long-term animal studies are essential for evaluating chronic toxicity before clinical trials. 7

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14


What is the name of the clinical trial phase mentioned for STEM-PD?

Phase I/IIa

Phase I/IIa trials assess both safety (Phase I) and preliminary efficacy (Phase IIa) in a small group of patients. Early clinical trial phases combine safety and initial effectiveness evaluation before larger studies. 7

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15


How is the STEM-PD product manufactured?

Under GMP-compliant conditions

Manufacturing under GMP-compliant conditions ensures quality, safety, and regulatory compliance for clinical use. Good Manufacturing Practice (GMP) standards are essential for producing safe and effective medical products. 7

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16


According to the article, what confirmed the safety of the STEM-PD product in rats?

There were no adverse effects or tumor formation.

The absence of adverse effects and tumor formation in rats indicates the product’s safety for further development. Preclinical safety studies focus on detecting toxicity and tumorigenicity before clinical trials. 7

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17


What key finding was noted in the efficacy study of STEM-PD in rats?

Transplanted cells reversed motor deficits in rats.

The transplanted stem cells successfully restored motor function, showing potential therapeutic effect for Parkinson’s disease. Stem cell therapy aims to replace lost neurons and improve functional deficits in neurodegenerative diseases. 7

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18


What specific markers were used to assess the purity of the STEM-PD batch?

GIRK2 and ALDH1A1

GIRK2 and ALDH1A1 are specific markers for mature dopamine neurons, indicating the purity of the stem cell batch. Using cell-type specific markers ensures the quality and identity of differentiated cells in stem cell therapy. 7

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19


What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?

They are used in cell patterning for specific neural fates.

FGF8b and SHH are growth factors that guide stem cells to develop into specific types of neurons by influencing cell patterning. Developmental biology shows these factors regulate neural differentiation and regional identity. 7

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20


What was a key outcome measured in the preclinical trials for efficacy in rats?

Recovery of motor function

Recovery of motor function indicates that the treatment helped repair neurological damage caused by Parkinson’s disease in rats. Recovery of motor function indicates that the treatment helped repair neurological damage caused by Parkinson’s disease in rats. 7

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ผลคะแนน 119.75 เต็ม 140

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