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1


What is hybrid micellar liquid chromatography primarily used for in the study?

To detect commonly used pesticides in vegetables.

The method is designed to be fast, reliable, and environmentally friendly, using small amounts of toxic chemicals. HMLC combines micellar liquid chromatography with reverse-phase chromatography to handle complex mixtures more effectively. 7

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2


Which pesticide was found most commonly in the vegetable samples?

Chlorpyrifos

Chlorpyrifos has the highest of all pesticides tested. Chlorpyrifos was detected in 76% of the analyzed green leafy vegetable samples. 7

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3


What percentage of the vegetable samples tested were found to contain no detectable pesticides?

16%

There are 16% of the green leafy vegetable samples tested with undetectable pesticides. There are small amount of imidacloprid, chlorpyrifos, profenofos, and cypermethrin in those vegetables. 7

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4


Which of the following is NOT a reason for the use of hybrid micellar liquid chromatography (HMLC)?

It requires extensive solvent use.

It need to use small amount of toxic chemicals. The purpose of using HMLC is to minimize the use of toxic organic solvents like acetonitrile or methanol. 7

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5


What was the primary methodological change in the HMLC technique used in the study?

Use of a micellar mobile phase with reduced solvent usage.

It is safer and cheaper to operate, more environmentally friendly, and effective for separating and detecting multiple pesticides. The use of a micellar mobile phase with low solvent consumption is the key innovation that defines HMLC method. 7

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6


According to the study, why might vegetable growers prefer other pesticides over Imidacloprid (ICP)?

ICP is more expensive.

Lower effectiveness and more expensive or less accessible. Growers may prefer pesticides like chlorpyrifos or profenofos over imidacloprid due to factors such as effectiveness, cost, availability, or local practice. 7

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7


What is the major benefit of using ICP as a pesticide, according to the study?

It is less toxic compared to many others.

It has strong activity against sucking insects like aphids, whiteflies, and leafhoppers. The major benefit of using ICP is its high effectiveness against target pests, offering systemic and sustained protection for crops. 7

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8


What aspect of the pesticide detection method was focused on during the method validation phase?

Ensuring it can detect extremely low pesticide levels.

It can sometimes detect nothing from the samples. The lowest concentration of each pesticide that could be reliably quantified, ranging from 0.09 to 0.25 mg/kg, depending on the compound. 7

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9


Considering the environmental impacts discussed, why is the HMLC method considered 'green'?

It involves less waste and uses low-toxicity solvents.

It decreases chemical waste, reducing hazardous issues. The HMLC method uses small solvent consumption and low toxic chemical, make it environmentally friendly, safer, and more sustainable compared to chromatographic methods. 7

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10


What is the importance of the photodiode array detector in the HMLC technique used in the study?

It detects the presence of pesticides across a spectrum of wavelengths.

It improves selectivity and identification. The PDA detector makes the HMLC method better by enabling accurate, sensitive, and reliable multi-compound detection through continuously spectral monitoring. 7

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11


What is hyperthermia commonly used to treat?

Cancer

It raises the temperature of body tissues to damage and kill cancer cells. Hyperthermia is primarily applied to treat various types of cancer by damaging tumor cells while sparing normal tissue. 7

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12


Which method is used to apply heat directly to a tumor in local hyperthermia?

Infrared radiation

Infrared waves can penetrate heat the tumor tissue under the skin surface. Infrared radiation is a useful local hyperthermia method, providing controlled heat application to help treat cancer better. 7

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13


What is the primary benefit of using hyperthermia in cancer treatment?

It kills cancer cells with minimal damage to normal cells.

It can directly damages or kills cancer cells without damaging normal cells. Hyperthermia boosts treatment by sensitizing cancer cells to radiation and chemotherapy and directly damaging tumor tissue. 7

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14


Hyperthermia is often used in combination with which of the following treatments?

Radiotherapy and chemotherapy

It increases cancer cells’ sensitivity to radiation and chemotherapy. It improves treatment effectiveness and may improve outcomes. 7

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15


What is the main challenge of using hyperthermia in cancer treatment?

Reaching and maintaining the required temperature in the target area.

Maintaining the target temperature uniformly within the tumor is difficult. The biggest challenge in hyperthermia therapy is accurate, controlled heating of the tumor while protecting normal tissues, which requires complex equipment. 7

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16


Which type of hyperthermia involves heating a larger region or the whole body?

Whole-body hyperthermia

Heating a larger area or the entire body is done through whole-body hyperthermia. Whole-body Hyperthermia raises the temperature of the entire body, and it is used for treating metastatic cancer or when cancer has spread widely. 7

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17


What type of hyperthermia uses applicators inserted into or near a body cavity to deliver heat?

Interstitial hyperthermia

Applicators are placed inside or very close to the tumor, such as in body cavities or tissues. Internal hyperthermia uses inserted applicators to deliver heat directly inside or near tumors via body cavities. 7

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18


What is a significant potential side effect of whole-body hyperthermia?

Systemic stress affecting major organs

Maintaining safe temperature levels requires careful monitoring and control. Whole-body hyperthermia has serious systemic side effects due to overheating of the entire body, requires careful clinical supervision. 7

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19


Considering the physics of heat transfer, why is controlling hyperthermia challenging during treatment?

Human tissue has varying thermal conductivities which affect heat distribution.

Controlling hyperthermia during treatment is challenging due to the complex heat transfer in biological tissues. The challenge is caused by variation in how biological tissues absorb, conduct, and dissipate heat, and the body actively cools itself, making it hard to achieve and maintain precise tumor temperatures during hyperthermia treatment. 7

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20


Why is hyperthermia considered a beneficial adjunct to radiotherapy and chemotherapy?

It makes cancer cells more susceptible to other treatments.

It improves effectiveness by making cancer cells more vulnerable to treatment. Hyperthermia improves the efficiency of radiotherapy and chemotherapy by increasing tumor oxygenation, preventing tumor repairing, directly damaging cancer cells, and overcoming tumor resistance. 7

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ผลคะแนน 119.75 เต็ม 140

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