| 1 |
What is the primary function of AI in the medical imaging industry?
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To reduce the cost of medical equipment |
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| 2 |
Which of the following is a key benefit of AI in radiology noted in the article?
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Reduces the speed of diagnosing |
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| 3 |
What does AI literacy refer to according to the article?
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Understanding and knowledge of AI technology |
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| 4 |
Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?
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The color of the AI machines |
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| 5 |
What role does social influence play in AI acceptability in healthcare according to the article?
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Affects healthcare professionals’ decisions to use AI |
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If Healthcare professionals decide to use AI, This will make AI look even more credible. |
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| 6 |
What is a perceived threat regarding AI usage in healthcare settings?
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Lesser patient interaction with doctors |
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However, I think it is important for patients to actually interact with their doctors. |
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| 7 |
According to the article, what is essential for increasing AI acceptability among medical professionals?
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Ensuring AI systems have high algorithmic performance |
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| 8 |
What does the 'system usage' category of AI acceptability factors include according to the article?
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User's personal preferences only |
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| 9 |
How does ethicality impact AI acceptability among healthcare professionals?
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Determines the pricing of AI systems |
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| 10 |
What methodological approach did the article emphasize for future AI acceptability studies?
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Considering user experience and system integration deeply |
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| 11 |
What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?
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To replace lost dopamine neurons. |
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Parkinson's disease is characterized by the degeneration and loss of dopamine-producing neurons in a specific area of the brain called the substantia nigra. |
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| 12 |
Which animal was used to test the STEM-PD product for safety and efficacy?
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Rats |
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These preclinical trials in rats provided crucial data supporting the safety and efficacy before the product moved into human clinical trials |
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| 13 |
What was the duration of the preclinical safety study in rats mentioned in the article?
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9 months |
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| 14 |
What is the name of the clinical trial phase mentioned for STEM-PD?
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Phase I |
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It is described as a "first-in-human" trial, which is characteristic of Phase 1 studies. Its primary aim is to assess the safety and tolerability of the STEM-PD product in people with Parkinson's disease |
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| 15 |
How is the STEM-PD product manufactured?
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Using spontaneous differentiation |
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The STEM-PD product is manufactured from human embryonic stem cells (hESCs). Specifically, it is a cryopreserved cell product consisting of ventral midbrain dopaminergic progenitor cells derived from a clinical-grade hESC line called RC17. |
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| 16 |
According to the article, what confirmed the safety of the STEM-PD product in rats?
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There were no adverse effects or tumor formation. |
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| 17 |
What key finding was noted in the efficacy study of STEM-PD in rats?
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Transplanted cells increased cognitive impairments. |
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| 18 |
What specific markers were used to assess the purity of the STEM-PD batch?
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OCT4 and NANOG |
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This is critical because undifferentiated cells carry a risk of teratoma formation (a type of tumor) after transplantation. Markers like OCT4 and NANOG |
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| 19 |
What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?
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They prevent differentiation. |
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| 20 |
What was a key outcome measured in the preclinical trials for efficacy in rats?
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Increase in anxiety-like behaviors |
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A common measure in unilateral lesion models where rats rotate towards the lesioned side. Effective treatment would reduce or eliminate this rotational bias |
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