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1


What is the primary function of AI in the medical imaging industry?

To improve diagnostic accuracy and patient outcomes

AI in medical imaging primarily improves diagnostic accuracy, and patient outcomes by analyzing to detect abnormalities enabling earlier and more precise diagnoses The Role of AI in Radiology : Transforming Healthcare 7

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2


Which of the following is a key benefit of AI in radiology noted in the article?

Acts as a second medical opinion

AI radiology acts as a second medical opinion by detecting patterns and anomalies and images enhancing diagnostic accuracy, and ensuring more precise diagnoses. Medical Imaging : AI as a second opinion 7

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3


What does AI literacy refer to according to the article?

Understanding and knowledge of AI technology

AI literacy refers to the ability to understand use monitor and critically reflect on AI applications. It involves recognizing AI technologies, grasping their functionality, using them effectively and critically assessing their impacts comprehensive understanding enables individuals to navigate the opportunities and challenges presented by AI in various context. And 7

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4


Which factor is NOT listed as influencing the acceptability of AI among healthcare professionals?

The color of the AI machines

The color of AI machines is not identified as a factor affecting their acceptability among healthcare professionals. 7

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5


What role does social influence play in AI acceptability in healthcare according to the article?

Affects healthcare professionals’ decisions to use AI

Social influence, a significant role in healthcare professionals decide whether to adopt and use AI tech technologies in healthcare settings. 7

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6


What is a perceived threat regarding AI usage in healthcare settings?

Lesser patient interaction with doctors

Concerns have been raised that AIT tools might reduce the amount of time doctor spend interacting with patients potentially affecting the quality of the doctor. Patient relationship some studies suggest that while I can assist in tasks like diagnosis, it should not replace human doctors as the human element is essential for effective patient care. These concerns highlight the importance of integrating AI in a way that complements and enhances human interaction in healthcare , rather than diminishing it. 7

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7


According to the article, what is essential for increasing AI acceptability among medical professionals?

Designing human-centred AI systems

Human centered, AI systems, prioritize, usability, and transparency, which are crucial for gaining trust and acceptance among medical professionals. 7

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8


What does the 'system usage' category of AI acceptability factors include according to the article?

Factors like value proposition and integration with workflows

The system usage category focuses on how well AI integrate with existing workflow and its perceived value in improving efficiency and effectiveness. 7

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9


How does ethicality impact AI acceptability among healthcare professionals?

Affects views on AI based on compatibility with professional values

Ethicality influences healthcare professionals, acceptance of AI by ensuring it aligns with their values such as safety, transparency, and fairness. 7

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10


What methodological approach did the article emphasize for future AI acceptability studies?

Considering user experience and system integration deeply

Focusing on user experience system integration AI with healthcare professional needs improving acceptance. 7

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11


What is the primary objective of using human embryonic stem cells in treating Parkinson’s disease?

To replace lost dopamine neurons.

The primary goal is to replace the dopamine pro producing neurons in the brain which are responsible for the symptoms of Parkinson’s disease. 7

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12


Which animal was used to test the STEM-PD product for safety and efficacy?

Rats

The STEM-PD product was tested for safety and efficacy in rat models. Mice are also commonly used in pre-clinical testing, but in the case of the stem PV product rats were specifically mentioned as the primary animal model for safety and testing while both rats and mice are used in such studies. The distinction often depends on the specific requirements of the research and the biological similarities to human conditions. In this instance, the focus was for testing the product 7

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13


What was the duration of the preclinical safety study in rats mentioned in the article?

9 months

The pre-clinical safety study of the stem PD product and rats lasted 39 weeks, which is approximately nine months this toxicity and bio distribution and no adverse effect observed 7

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14


What is the name of the clinical trial phase mentioned for STEM-PD?

Phase I/IIa

The stampede clinical trial is in phase I/IIa .This first in human trial focuses on assessing the safety and feasibility of using a stem cell product to treat Parkinson’s disease patients. 7

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15


How is the STEM-PD product manufactured?

Under GMP-compliant conditions

The STEM-PD product is manufactured under GMP compliant conditions. This ensures that the stem cell derived dopamine producing neurons are produced in a controlled environment at a good manufacturing practice standards to maintain product, quality and safety. 7

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16


According to the article, what confirmed the safety of the STEM-PD product in rats?

There were no adverse effects or tumor formation.

In a 39 week rat safety study. The product was tested for toxicity, tonicity, and bio distribution, and no adverse effects were observed. 7

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17


What key finding was noted in the efficacy study of STEM-PD in rats?

Transplanted cells reversed motor deficits in rats.

In preclinical studies, transplanted, STEM-PD cells matured into dopamine producing neurons effectively reversing motor deficits in animal models of Parkinson’s disease. These findings suggest that STEM-PD has the potential to restore motor function by replacing dopamine, producing neurons and Parkinson’s disease patientsS. 7

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18


What specific markers were used to assess the purity of the STEM-PD batch?

GIRK2 and ALDH1A1

The specific markers used to assess the purity of the STEM-PD batch are GIRK2 and ALDH1A1. These markers are typically used to assess dopamine uric neuronal differentiation, suggesting that the cells have differentiated into a dopamine lineage. 7

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19


What role do growth factors like FGF8b and SHH play in the manufacturing process of STEM-PD?

They are used in cell patterning for specific neural fates.

FGF8b and SHH help guide stem cells to differentiate into specific neural types, including dopamine and uric neurons during the manufacturing process of STEM-PD. 7

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20


What was a key outcome measured in the preclinical trials for efficacy in rats?

Recovery of motor function

A key outcome measured in pre-clinical trials for efficacy and rats is recovery of motor function. This is commonly assessed to evaluate the effectiveness of treatments on neurological or physical conditions that affect movement. 7

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ผลคะแนน 63.05 เต็ม 140

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