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What is the main advantage of using nanomaterials in electrochemical sensors for medical diagnostics?
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3. They enhance sensitivity and surface area for detection |
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Nanomaterials have an extremely high surface-area-to volume ratio, which means more area is available for biological molecules to interact with sensor.
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From the Abstract of the paper, “Nanotechnology-enhanced sensors offer remarkable improvements in sensitivity, specificity, miniaturization, and making them ideal for point-of-care testing and real-time analysis.
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Which of the following nanomaterials is frequently mentioned as enhancing sensor conductivity?
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2. Gold nanoparticles |
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Gold Nanoparticles facilitate fast electron transfer and amplify electrochemical signals, making them ideal for improving sensitivity in diagnostic sensors.
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Gold Nanoparticles are frequently mentioned in the review article as a key nanomaterial that enhances the electrical conductivity of electrochemical sensors.
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Why are carbon-based nanomaterials such as carbon nanotubes (CNTs) useful in electrochemical sensors?
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3. They improve electron transfer and mechanical strength |
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Carbon nanotubes possess exceptional electrical conductivity, enabling efficient electron transfer between the analyte and the electrode surface, which is crucial for high-sensitivity detection in electrochemical sensors.
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CNTs have excellent electrical conductivity and large surface area, which help speed up electron transfer and provide strong mechanical support, leading to better sensor performance.
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4 |
What is one challenge in integrating nanotechnology with electrochemical sensors for medical use?
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3. Issues in reproducibility and standardization |
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This affects the reliability, consistency, and scalability of nanomaterial-based sensors, making clinical translation and commercial production more difficult.
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Reference from the article, “ Despite the outstanding performances of nanomaterial-based electrochemical sensors, the lack of reproducibility and standardization in sensor fabrication hinders their clinical translation. “
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5 |
Which technique is commonly used to enhance the signal in nanotechnology-based electrochemical sensors?
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2. Enzyme labeling |
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Enzyme labeling enhances the electrochemical signal by catalyzing redox reactions that produce measurable currents, improving sensor sensitivity.
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From, “ Enzyme labeling is a commonly employed signal amplification strategy, where enzymes such as HRPae used to catalyze redox reactions, thereby enhancing the electrochemical signal. “
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6 |
Why is biocompatibility crucial in designing electrochemical sensors for medical diagnostics?
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2. To prevent rejection or toxicity in biological systems |
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Biocompatibility is essential is in medical electrochemical sensors to avoid immune responses, inflammation, or toxicity when the sensor interacts with biological fluids or tissues. A biocompatible sensor enssures safe, accurate, long-term use in clinical settings.
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Reference from the article, “ Biocompatibility is crucial to avoid toxicity and adverse reactions when sensors interact with biological environments. “
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7 |
How do label-free electrochemical sensors differ from labeled ones?
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3. They do not rely on additional reagents or markers |
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Label-free sensors detect target molecules directly through changes in electrical signals without using enzymes, dyes, o fluorescent markers. This makes the process simpler, faster, and cost-effective, with minimal sample preparation.
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Reference from the article, “ Label-free sensors detect biomolecules without the need for additional labeling agents, allowing for direct and real-time analysis. “
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8 |
What is one promising application of nanotech-based electrochemical sensors?
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Nanotechnology-based electrochemical sensors are highly sensitive and selective, making them ideal for early detection of disease biomarkers. This allows for faster diagnosis and improved treatment outcomes in disease.
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“ Nanomaterial-enhanced electrochemical sensors offer great potential for early detection of disease biomarkers, contributing to timely diagnosis and personalized medicine. “
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9 |
Which of the following factors most directly affects the sensor's detection limit?
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2. Nanomaterial surface-to-volume ratio |
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A higher surface-to-volume ratio in nanomaterials increases the number of active sites available for target molecules directly through interaction, which significantly enhances sensitivity and lowers the detection limit of the sensor.
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“ The large surface-to-volume ratio of nanomaterials allows or greater interaction with analytes, thereby improving sensitivity and lowering detection limits. “
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10 |
What is one of the primary goals of using digital sensing technologies in cancer care?
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3. Enable earlier and more personalized diagnosis |
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Digital sensing tehnologies in career care aim to detect cancer-related biomarkers early and provide personalized diagnostic data.
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” Digital sensing enables early detection and facilities personalized diagnosis, which is essential for timely and effective cancer treatment. “
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11 |
Which type of sensor is often used to monitor physical activity in cancer patients?
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3. Accelerometers |
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Accelerometers are commonly used to monitor physical activity and movement patterns in cancer patients.
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“ Wearable accelerometers are widely used to assess physical activity levels in cancer patients, aiding in monitoring fatigue. And overall health status. “
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12 |
Why are patient-reported outcomes important in digital cancer care systems?
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3. They provide subjective data complementing sensor metrics |
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Patient-reported outcomes add subjective insights that sensors can’t capture, improving personalized care when combined with sensor data.
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It notes that integrating biosensor data with patient-reported information can enhance diagnostic accuracy and decision-making, especially in personalized medicine.
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13 |
What is one major advantage of real-time digital sensing in cancer treatment?
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3. Rapid detection of deterioration in patient condition |
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Real-time digital sensing allows continuous monitoring of patients, enabling healthcare providers to quickly identify any worsening symptoms or complications during cancer treatment, which supports timely interventions.
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” Nanomaterials-based electrochemical sensors facilitate fast and sensitive detection of disease biomarkers, enabling real-time monitoring critical for early diagnosis and management of health deteriorating. “
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Which of the following is a key barrier to implementing digital sensing in routine oncology practice?
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4. Overabundance of clinical evidence |
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Many patients and healthcare providers may lack the necessary skills to effectively use and interpret digital health technologies.
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The article highlights challenges such as limited user familiarity and training as key hurdles for widespread clinical adoption of nanotechnology-enabled sensors and digital diasnostics.
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15 |
Which stakeholders are considered central to the adoption of digital cancer care platforms?
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2. Patients and healthcare providers |
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The successful adoption of digital cancer care platforms relies heavily on the engagement from both patients, who use the technologies, and healthcare providers, who interpret and act on the data.
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In the section on implementation challenges, it states, “Key stakeholders central to adoption include patients and healthcare providers, whose digital literacy and acceptance significantly influence uptake. “
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16 |
Digital sensing systems collect which combination of data types for cancer care optimization?
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2. Sensor metrics and patient-reported outcomes |
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The article highlights that digital sensing systems combine objective sensor data with subjective patient-reported outcomes to provide a comprehensive view for cancer care optimization.
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It states, “ Integation of sensor-generated metrics with patients-reported outcome allows for personalized monitoring and management in cancer care. “
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17 |
How do digital sensors contribute to improving the quality of life in cancer patients?
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3. By enabling symptom tracking and early intervention |
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The article explains that digital sensors improve quality of life by continuously monitoring symptoms.
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It mentions, “ Digital sensing facilities real-time symptom tracking, enabling prompt responses that can improve patient outcomes and quality of life. “
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What does the article suggest about the future direction of digital sensing in cancer care?
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3. It holds promise for widespread personalized care |
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The article suggests that digital sensing technologies are expected to play a major role in the future of personalized cancer care by enabling tailored interventions based on real-time, individual data.
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It states, “ The future of digital sensing in oncology lies in its potential to deliver scalable, personalized care through continuous and context-aware monitoring. “
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19 |
Based on the diagram, which of the following would most likely result in a false signal output in an electrochemical sensor for medical diagnostics?
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2. Increasing the number of bioreceptors without sample optimization |
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Increasing the number of bioreceptors without properly optimizing for the sample can lead to non-specific binding.
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Electrochemical sensors rely on specific biomolecular recognition between the bioreceptors and the analyte.
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20 |
Based on the image, which of the following scenarios best demonstrates the advantage of using emerging digital platforms in cancer diagnostics?
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3. A portable chip-based sensor detects protein biomarkers from a blood sample within minutes |
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It eliminates the need for time-consuming lab work, making diagnosis faster and more efficient.
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This scenario is based on the principle of biosensors.
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