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1


What is the main advantage of using nanomaterials in electrochemical sensors for medical diagnostics?

3. They enhance sensitivity and surface area for detection

Nanomaterials have an extremely high surface-area-to volume ratio, which means more area is available for biological molecules to interact with sensor.

From the Abstract of the paper, “Nanotechnology-enhanced sensors offer remarkable improvements in sensitivity, specificity, miniaturization, and making them ideal for point-of-care testing and real-time analysis.

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2


Which of the following nanomaterials is frequently mentioned as enhancing sensor conductivity?

2. Gold nanoparticles

Gold Nanoparticles facilitate fast electron transfer and amplify electrochemical signals, making them ideal for improving sensitivity in diagnostic sensors.

Gold Nanoparticles are frequently mentioned in the review article as a key nanomaterial that enhances the electrical conductivity of electrochemical sensors.

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3


Why are carbon-based nanomaterials such as carbon nanotubes (CNTs) useful in electrochemical sensors?

3. They improve electron transfer and mechanical strength

Carbon nanotubes possess exceptional electrical conductivity, enabling efficient electron transfer between the analyte and the electrode surface, which is crucial for high-sensitivity detection in electrochemical sensors.

CNTs have excellent electrical conductivity and large surface area, which help speed up electron transfer and provide strong mechanical support, leading to better sensor performance.

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4


What is one challenge in integrating nanotechnology with electrochemical sensors for medical use?

3. Issues in reproducibility and standardization

This affects the reliability, consistency, and scalability of nanomaterial-based sensors, making clinical translation and commercial production more difficult.

Reference from the article, “ Despite the outstanding performances of nanomaterial-based electrochemical sensors, the lack of reproducibility and standardization in sensor fabrication hinders their clinical translation. “

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5


Which technique is commonly used to enhance the signal in nanotechnology-based electrochemical sensors?

2. Enzyme labeling

Enzyme labeling enhances the electrochemical signal by catalyzing redox reactions that produce measurable currents, improving sensor sensitivity.

From, “ Enzyme labeling is a commonly employed signal amplification strategy, where enzymes such as HRPae used to catalyze redox reactions, thereby enhancing the electrochemical signal. “

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6


Why is biocompatibility crucial in designing electrochemical sensors for medical diagnostics?

2. To prevent rejection or toxicity in biological systems

Biocompatibility is essential is in medical electrochemical sensors to avoid immune responses, inflammation, or toxicity when the sensor interacts with biological fluids or tissues. A biocompatible sensor enssures safe, accurate, long-term use in clinical settings.

Reference from the article, “ Biocompatibility is crucial to avoid toxicity and adverse reactions when sensors interact with biological environments. “

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How do label-free electrochemical sensors differ from labeled ones?

3. They do not rely on additional reagents or markers

Label-free sensors detect target molecules directly through changes in electrical signals without using enzymes, dyes, o fluorescent markers. This makes the process simpler, faster, and cost-effective, with minimal sample preparation.

Reference from the article, “ Label-free sensors detect biomolecules without the need for additional labeling agents, allowing for direct and real-time analysis. “

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8


What is one promising application of nanotech-based electrochemical sensors?

Nanotechnology-based electrochemical sensors are highly sensitive and selective, making them ideal for early detection of disease biomarkers. This allows for faster diagnosis and improved treatment outcomes in disease.

“ Nanomaterial-enhanced electrochemical sensors offer great potential for early detection of disease biomarkers, contributing to timely diagnosis and personalized medicine. “

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9


Which of the following factors most directly affects the sensor's detection limit?

2. Nanomaterial surface-to-volume ratio

A higher surface-to-volume ratio in nanomaterials increases the number of active sites available for target molecules directly through interaction, which significantly enhances sensitivity and lowers the detection limit of the sensor.

“ The large surface-to-volume ratio of nanomaterials allows or greater interaction with analytes, thereby improving sensitivity and lowering detection limits. “

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10


What is one of the primary goals of using digital sensing technologies in cancer care?

3. Enable earlier and more personalized diagnosis

Digital sensing tehnologies in career care aim to detect cancer-related biomarkers early and provide personalized diagnostic data.

” Digital sensing enables early detection and facilities personalized diagnosis, which is essential for timely and effective cancer treatment. “

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11


Which type of sensor is often used to monitor physical activity in cancer patients?

3. Accelerometers

Accelerometers are commonly used to monitor physical activity and movement patterns in cancer patients.

“ Wearable accelerometers are widely used to assess physical activity levels in cancer patients, aiding in monitoring fatigue. And overall health status. “

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12


Why are patient-reported outcomes important in digital cancer care systems?

3. They provide subjective data complementing sensor metrics

Patient-reported outcomes add subjective insights that sensors can’t capture, improving personalized care when combined with sensor data.

It notes that integrating biosensor data with patient-reported information can enhance diagnostic accuracy and decision-making, especially in personalized medicine.

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13


What is one major advantage of real-time digital sensing in cancer treatment?

3. Rapid detection of deterioration in patient condition

Real-time digital sensing allows continuous monitoring of patients, enabling healthcare providers to quickly identify any worsening symptoms or complications during cancer treatment, which supports timely interventions.

” Nanomaterials-based electrochemical sensors facilitate fast and sensitive detection of disease biomarkers, enabling real-time monitoring critical for early diagnosis and management of health deteriorating. “

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14


Which of the following is a key barrier to implementing digital sensing in routine oncology practice?

4. Overabundance of clinical evidence

Many patients and healthcare providers may lack the necessary skills to effectively use and interpret digital health technologies.

The article highlights challenges such as limited user familiarity and training as key hurdles for widespread clinical adoption of nanotechnology-enabled sensors and digital diasnostics.

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15


Which stakeholders are considered central to the adoption of digital cancer care platforms?

2. Patients and healthcare providers

The successful adoption of digital cancer care platforms relies heavily on the engagement from both patients, who use the technologies, and healthcare providers, who interpret and act on the data.

In the section on implementation challenges, it states, “Key stakeholders central to adoption include patients and healthcare providers, whose digital literacy and acceptance significantly influence uptake. “

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16


Digital sensing systems collect which combination of data types for cancer care optimization?

2. Sensor metrics and patient-reported outcomes

The article highlights that digital sensing systems combine objective sensor data with subjective patient-reported outcomes to provide a comprehensive view for cancer care optimization.

It states, “ Integation of sensor-generated metrics with patients-reported outcome allows for personalized monitoring and management in cancer care. “

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17


How do digital sensors contribute to improving the quality of life in cancer patients?

3. By enabling symptom tracking and early intervention

The article explains that digital sensors improve quality of life by continuously monitoring symptoms.

It mentions, “ Digital sensing facilities real-time symptom tracking, enabling prompt responses that can improve patient outcomes and quality of life. “

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18


What does the article suggest about the future direction of digital sensing in cancer care?

3. It holds promise for widespread personalized care

The article suggests that digital sensing technologies are expected to play a major role in the future of personalized cancer care by enabling tailored interventions based on real-time, individual data.

It states, “ The future of digital sensing in oncology lies in its potential to deliver scalable, personalized care through continuous and context-aware monitoring. “

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19


Based on the diagram, which of the following would most likely result in a false signal output in an electrochemical sensor for medical diagnostics?

2. Increasing the number of bioreceptors without sample optimization

Increasing the number of bioreceptors without properly optimizing for the sample can lead to non-specific binding.

Electrochemical sensors rely on specific biomolecular recognition between the bioreceptors and the analyte.

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20


Based on the image, which of the following scenarios best demonstrates the advantage of using emerging digital platforms in cancer diagnostics?

3. A portable chip-based sensor detects protein biomarkers from a blood sample within minutes

It eliminates the need for time-consuming lab work, making diagnosis faster and more efficient.

This scenario is based on the principle of biosensors.

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ผลคะแนน 119.75 เต็ม 140

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