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ใช้เวลาสอบ 57 นาที

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# คำถาม คำตอบ ถูก / ผิด สาเหตุ/ขยายความ ทฤษฎีหลักคิด/อ้างอิงในการตอบ คะแนนเต็ม ให้คะแนน
1


What percentage of the PCPs examined contained UV filters?

58%

PCPs contain UV filters

PCPs contain UV filters in order to protect one’s skin from the harmful effects of UV light, which can potentially cause skin cancer and/or wrinkling. UV filters were used in 58% of the PCPs (Sebatane Sharon Mabitla Natsayi Chiwaye Michael O. Daramola )

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2


Which of the following is NOT a category of PCPs mentioned in the study?

Hair care products

Personal care products (PCPs) comprise a wide range of chemicals employed in various products such as cleansers, toothpaste, sunscreens,make up and skincare

A total of 185 PCPs were examined, with 57% of these products classified as skincare, 32% as rinse-off products and 11% as make-up products. (Sebatane Sharon Mabitla Natsayi Chiwaye Michael O. Daramola )

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3


Which ingredient is commonly used as a preservative in PCPs?

Phenoxyethanol

phenoxyethanol was found in skincare products and make-up

Phenoxyethanol (47.8%) is the most dominant preservative used in PCPs found in South Africa as analysed in this study. In reference to Table 3 above, phenoxyethanol was found in 35 skincare products and also in 5 make-up products (Sebatane Sharon Mabitla Natsayi Chiwaye Michael O. Daramola )

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4


What was the primary aim of the study discussed in the article?

To investigate the presence of toxic chemical ingredients in PCPs

because PCPs are a component of many chemicals

ersonal Care Products (PCPs) contain a wide range of chemicals which cleanse or enhance one’s body appearance. These chemicals are continuously released into the environment, and if not properly regulated, they can be persistent, bioaccumulative and toxic in the environment. (Sebatane Sharon Mabitla Natsayi Chiwaye Michael O. Daramola )

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5


Which of the following fragrances is considered a weak allergen but found frequently in PCPs?

Limonene

limonene is found 73.3%

the most frequently identified fragrances were limonene (73.3%), linalool (69.2%), coumarin (40%), hexyl cinnamal (38.3%), benzyl alcohol (35%) and citral (28.3%). These fragrances are reportedly weak allergens this explains their high occurrence in most of the PCPs.

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6


What does the term 'emerging pollutants' refer to in the context of the study?

Pollutants that have recently been discovered and may not degrade easily

These chemicals are continuously released into the environment, and if not properly regulated, they can be persistent, bioaccumulative and toxic in the environment.

emerging evidence suggests that some accumulate in body tissues and negatively impact humans and animals, impacting the endocrine systems and the environment since they are continuously being released and may not degenerate easily the environment. The contaminants are thus called emerging pollutants.

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7


What percentage of skin care products examined contained fragrances?

69.5%

In reference to Table 1 in the study

skin care products examined contained fragrance 69.5% or have number 73

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8


According to the study, which substance is toxic to aquatic life and can affect fertility?

Alpha-isomethyl ionone

Alpha-isomethyl ionone is harmful to the environment and restricted by regulatory bodies

These include harmful fragrances such alpha-isomethyl ionone and butylphenyl methylpropional, which were found to be present in over 16% of the studied PCPs

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9


Based on the study, which regulatory action is recommended due to the detection of harmful ingredients in PCPs despite their ban?

More stringent regulations on product labelling and testing

because Some manufacturers place PCPs in the market with missing ingredient information

objective of the current study was to examine PCP ingredients, as listed on the product labels

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10


What are the potential health risks associated with chemicals in PCPs as mentioned in the study?

Both 1 and 2

The great consumption of these products has led to their continuous release into the environment, which consequently threatens ecosystems and human health

The reported health risks associated with chemical ingredients in PCPs (such as ultraviolet (UV) filters, parabens, and phthalates) include potential endocrine disruption and exhibition of estrogenic activity

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11


What is the primary purpose of Process Analytical Technology (PAT)?

To monitor process parameters and product quality attributes.

Process Analytical Technology (PAT) is a system that focuses on controlling and enhancing the understanding of a production process

PAT's primary goal is to measure critical process parameters (CPPs) that directly impact the essential quality attributes of active pharmaceutical ingredients (APIs).

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12


Which technology is often combined with reliable in-line sensors to enhance PAT systems?

Multivariate Statistical Methods (MSMs).

spectroscopic instruments and Multivariate Statistical Methods (MSMs)

PAT systems include a combination of reliable in-line sensors, spectroscopic instruments and Multivariate Statistical Methods (MSMs) to provide informative knowledge for quality assessment of powdered and granule products

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13


What does data fusion primarily help improve in PAT systems?

Increase performance and robustness of models.

data fusion were proposed to help model performance

data fusion approaches were hope to improve the model performance for assessing a wide range of CQAs.

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14


Which is NOT a listed advantage of continuous processing of powdered and granule products?

Decreased safety standards.

it can improve productivity, product quality and financial services.

Continuous processing of powdered and granule products has advantages in improved productivity, product quality and financial services.

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15


Which of the following is considered a Critical Quality Attribute (CQA) for powdered and granule products?

Particle size.

particle size is one of the consideration

it has homogeneity, particle size, flowability, bulk density, particle strength, moisture content and particle shape

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16


What does the integration of multiple unit operations in one production system characterize?

Continuous processing of powdered and granule products comprising

Continuous processing of powdered and granule products comprising the integration of multiple unit operations in one production system

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17


What challenge does the article highlight about handling granular materials?

Hindered by complex material attributes.

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18


Which approach is specifically mentioned as useful for handling large analytical datasets in continuous processes?

Data fusion.

data fusion is useful for handling large analytical datasets in continuous processes

data fusion could be utilized in the field of PAT for an efficient handling of large analytical datasets in continuous processes.

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19


What does the future perspective section suggest about the integration of PAT and multi-sensor data fusion

It holds potential for enhancing real-time monitoring and control systems.

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20


Which technique is mentioned as crucial for designing, analyzing, and controlling manufacturing through monitoring?

Multivariate Statistical Methods (MSMs).

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ผลคะแนน 111.8 เต็ม 140

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