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EMPA หรือ SOTA ช่วยเพิ่มระยะการเคลื่อนที่ได้อย่างมีนัยสำคัญเท่าใด?

In zebrafish with a heart condition (DM-HFrEF), their swimming activity went down a lot 24 hours after getting a certain treatment (TER), more so than fish without the heart condition or those with the condition but no treatment. When they were given a higher dose (5 μM) of EMPA or SOTA, their swimming improved noticeably. However, there wasn't a big change in swimming when they got lower doses (0.2, 1, and 25 μM) of EMPA or SOTA.

Comparison of the effects of empagliflozin and sotagliflozin on a zebrafish model of diabetic heart failure with reduced ejection fraction Author: Inho Kim, Hyun-Jai Cho, Soo Lim, Seung Hyeok Seok and Hae-Young Lee.

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The pmcgs สามารถระบุได้อย่างชัดเจน ข้อใดกล่าวถูกต้อง

Scientists found that certain things called mcgs, spls, and pos are always there in both humans and chimpanzees. When scientists talk about certain lines on the brain, they often use "pre" or "post" if they're in front of or behind other important lines (like precentral, postcentral, and central lines). In this case, they're calling one of these lines the premarginal branch of the cingulate sulcus, or pmcgs for short. They could see the pmcgs in 97.22% of the left side and 94.4% of the right side of human brains, and in 100% of chimpanzee brains.

1. Sulcal morphology of posteromedial cortex substantially differs between humans and chimpanzees Author: Ethan H. Willbrand, Samira A. Maboudian, Joseph P. Kelly, Benjamin J. Parker, Brett L. Foster & Kevin S. Weiner

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P. knowlesi มี Pathway แบบใด

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จากบทความเรื่อง COVID-19 The NEMI pictogram presents four quadrants including?

The National Environmental Method Index (NEMI) is a tool created by the Methods and Data Comparability Board (MDCB) to check how environmentally friendly something is. It's been around for a long time and is used a lot. NEMI looks at four things—persistent, bio-accumulative, and toxic (PBT), corrosive, hazardous, and waste—to figure out how good or bad something is for the environment.

Green Assessment of Chromatographic Methods Used for the Analysis of Four Methamphetamine Combinations with Commonly Abused Drugs Author: Saif A. Alharthy,Muath A. Alharthi, Sultan A. Almalki, Sattam H. Alosaimi, Abdullah H. Aqeel , Sultan A. Altowairqi,Izzeddin Alsalahat,Dibya Sundar Panda,Mona Y. Alsheikh and Ibrahim A. Naguib

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จากบทความ cancer ที่ให้ไป the median HRD score for OV, UCS, LUSC, and ESCA is over

In different types of cancer, the HRD score (a measure of how messed up the DNA is) can be very different. For some, like thyroid (THCA) and acute myeloid leukemia (LAML), it's really low at zero. But for others, like ovarian (OV), uterine carcinosarcoma (UCS), lung squamous cell carcinoma (LUSC), and esophageal (ESCA), it's over 30. What's interesting is that even for people with the same type of cancer, their HRD scores can be quite different.

Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types Author: Zhiwen Shi, Bolin Chen, Xiao Han, Weiyue Gu, Shuzhi Liang, and Lin Wu

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ข้อใดเกี่ยวข้องกับการรักษาเสถียรภาพทางพันธุกรรมมากที่สุด

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ข้อใดไม่เข้าพวก topics ใน Epigenetics

Non-coding RNAs are like helpful tools in the way our genes work, especially in how our brains grow and work. There are different ways genes are controlled, and one big way is through something called epigenetics. It's like the set of instructions that tells genes when to turn on or off. When we talk about memory, scientists have looked a lot at how tiny changes happen to proteins (histones) and how the genetic material (chromatin) is arranged. One well-known way genes get instructions is through a process called DNA methylation, which has been the easiest to study using our current technology.

1. Non-coding RNAs in genome integrity Author: Igor Kovalchuk 2. Epigenetic regulation and chromatin remodeling in learning and memory Author: Somi Kim & Bong-Kiun Kaang 3. Epigenetics: The Science of Change Author: Bob Weinhold

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ข้อใดไม่ใช่หลักการของ DNA metabolism

DNA assembly is a really important tool in Synthetic Biology. When we can easily combine different pieces of DNA in one go, it helps us quickly create new and designed DNA structures.

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes Author: C.A. Merrick, C. Wardrope, J.E. Paget, S.D. Colloms , S.J. Rosser

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มีงานวิจัยใหม่ว่าระบบ CRISPR-cas system สามารถใช้เพื่อ knock out gene ได้ นักเรียนคิดว่าวิธีใดถูกต้อง

the developed CRISPR Primer Designer allows users to set the search range of The CRISPR Primer Designer lets you decide where to look for specific DNA parts (PAMs) and how much of the DNA should be made of a certain building block (GC content) for the CRISPR process. These choices are handy if you want to create a really big change in a gene or if you're aiming to edit a specific part of the gene, like a special area or structure. CRISPR-del, another tool we have, uses Cas9 and two guide RNAs to remove a big chunk of the gene. CRISPR-del is like a genetic scissors that uses Cas9 and two guide RNAs to cut out a big piece of the chromosome between these two specific places. This guarantees that the entire gene is turned off, or "knocked out."

1. A CRISPR-del-based pipeline for complete gene knockout in human diploid cells Author: Takuma Komori, Shoji Hata, Akira Mabuchi, Mariya Genova, Tomoki Harada, Masamitsu Fukuyama, Takumi Chinen, and Daiju Kitagawa 2. CRISPR Primer Designer: Design primers for knockout and chromosome imaging CRISPR-Cas system Author: Meng Yan, Shi-Rong Zhou and Hong-Wei Xue

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ข้อใดคือลจากการผิดพลาดของกระบวนการ DNA replication

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จากบทความในหัวข้อ Risk factors from environment อยากทราบว่า Epidemiological triad modified to structure possible disease determinants relevant for ASF occurrence มีอะไรบ้าง

The three main things that usually cause a disease are the environment, the host (which means the living thing that can get sick), and the pathogen (the thing causing the sickness) - this trio is called the epidemiological triad. For different diseases, we can add more details to these three parts based on what the disease is like. In the case of African Swine Fever (ASF), researchers grouped the factors that could cause it into different categories based on how they contribute to the risk of the disease.

1. CAUSES Author: KENNETH J. ROTHMAN 2. Veterinary Epidemiology Author: Michael Thrusfield

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จากบทความในหัวข้อ Climate change อยากทราบว่าจาก Figure 1. Research ในปีใดมีมากที่สุด

Look at Figure 1. It tells us how many papers about climate change were published each year from 1980 to 2014, according to the WoS database. The total number of papers in WoS, from 1980 to 2012, doubled about every 24 years. This means the number of publications about climate change is increasing really fast.

Climate Change Research in View of Bibliometrics Author: Robin Haunschild ,Lutz Bornmann,Werner Marx

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จากบทความ Fruit, vegetable, and fruit juice consumption and risk of gestational diabetes mellitus: a systematic review and meta-analysis The following criteria were used to determine which studies to include in the meta-analysis except?

We used PECOs to guide our study selection. Eligible participants were pregnant women aged 18 and above(Participant) . We focused on the intake of fruits, vegetables, and fruit juice as exposures. GDM criteria included self-reported clinical diagnosis or specific blood glucose levels after a glucose tolerance test (outcome). We mainly considered cohort studies (study design).

Fruit, vegetable, and fruit juice consumption and risk of gestational diabetes mellitus: a systematic review and meta-analysis Author: Yan-Ping Liao, Qing-Xiang Zheng, Xiu-Min Jiang, Xiao-Qian Chen, Xiao-Xia Gao & Yu-Qing Pan

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จากการอ่านบทความเรื่อง Plastic wastes in the time of COVID-19: Their environmental hazards and implications for sustainable energy resilience and circular bio-economies What analysis is used The potential of plastic waste as feedstock in biorefinery with respect to the circular economy along with the issues covering environmental footprint, human health, and SDGs?

Because of how much medical waste was thrown away during the pandemic, it's estimated that the amount of plastic waste doubled in 2020, reaching 630 million tons.

Plastic wastes in the time of COVID-19: Their environmental hazards and implications for sustainable energy resilience and circular bio-economies Author: Prabhat Kumar Rai,a C. Sonne,b H. Song,c and Ki-Hyun Kimd

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จากการอ่านบทความเรื่อง Effect Modification between Genes and Environment and Parkinson's Disease Riskอยากทราบว่า gene ใดมีผลกับ Cystic Fibrosis

Grasemann and colleagues found that certain differences in the nitric oxide synthase 1 (NOS1) gene are connected to how often and how serious infections can be. This suggests that the environment and variations in the NOS1 gene can work together.

Effect Modification between Genes and Environment and Parkinson’s Disease Risk Author: Maria Teresa Periñan Ph.D., Kajsa Brolin, MSc, Sara Bandres-Ciga, PhD,Cornelis Blauwendraat, Ph.D., Christine Klein, MD, Ph.D., Ziv Gan-Or, MD, PhD, Andrew Singleton, Ph.D., Pilar Gomez-Garre, Ph.D., Maria Swanberg, PhD, Pablo Mir, MD, Ph.D., and Alastair Noyce, MD, PhD

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จงอ่านข้อความต่อไปนี้แล้วตอบคำถาม A 47-year-old woman presents to her oncologist with the complaint of solid mass on ovarian mass. During her workup, an ultrasound of her breast shows a 6-cm right ovarian mass. อยากทราบต้องตรวจหาอะไรเพิ่มเติมจากเคสนี้

Massive ovarian edema is a rare condition in women of reproductive age. Because there are no clear signs in clinical, radiological, or biochemical tests, it's important to highlight the role of a test called intraoperative frozen section. This test can help doctors make decisions during surgery, like untwisting the ovary, making small cuts, or removing excess fluid. These procedures can help save the hormonal functions and fertility of young women with this condition.

A clinical update on massive ovarian oedema – a pseudotumor? Author: RS Praveen, VR Pallavi, K Rajashekar, A Usha, K Umadevi and UD Bafna

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จงอ่านข่าวต่อไปนี้แล้วตอบคำถาม ขาหนีบบวม สัมผัสแล้วพบก้อนใต้ผิวหนังแต่ไม่ก่อให้เกิดอาการปวดแต่อย่างใด • มีไข้ • น้ำหนักตัวลด • เหงื่อออกตอนกลางคืน • มีก้อนตามร่างกาย ป่วยเป็นโรคอะไร เพราะอะไร

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อาการเคี้ยวอาหาร กลืนอาหารลำบาก อยากทราบว่าผู้ป่วยคนนี้เป็นโรคอะไร เพราะเหตุใด

People with primary brain tumors who have difficulty swallowing may face more serious swallowing problems than they realize. This puts them at risk of breathing in food or drink and having nutritional issues. We suggest that these patients get a thorough assessment of their swallowing and then consider rehabilitation or using different ways of feeding to improve their situation.

Swallowing assessment in primary brain tumor patients with dysphagia Author: Herbert B. Newton, Cheryl Newton, Dennis Pearl, Tracy Davidson

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มีเลือดปนในอุจจาระ อาเจียน โดยอาจมีอาเจียนเป็นเลือดได้ อยากทราบว่าผู้ป่วยมีภาวะใด เพราะเหตุใด

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อาการชาที่แขนซ้ายเฉียบพลันสามารถเป็นอาการของโรคใด